Skeletal Muscle Undergoes Repair and Regenaration Throughout Free Essays

|21 | Coursework R: Mini-Review Topic Selected: Topic 2: â€Å"Skeletal muscle undergoes repair and regenaration throughout normal life. Write a review on the processes involved, emphasizing the role of satellite cells. † Muscle Cell Regeneration and the Impact of Ageing Introduction: Throughout normal life, skeletal muscles undergo repair and regeneration in response to injury through a process involving several sequential steps. We will write a custom essay sample on Skeletal Muscle Undergoes Repair and Regenaration Throughout or any similar topic only for you Order Now A very important role in this regeneration is played by satellite cells, which are small mononuclear progenitor cells found in mature muscle tissues. In this review, we are going to explore the consequences of ageing in satellite cell numbers and their ability to maintain and preserve muscle tissue. Steps involved when skeletal muscle is damaged: The homeostatic process that allows muscle regeneration in response to an injury stimulus, involves four interrelated steps: degeneration, inflammation, regeneration and remodelling repair. When myofibers are damaged, extracellular calcium flows into the cell, initiating proteolysis, which causes necrosis. The necrosis of myofibers brings about an inflammatory response where neutrophils and macrophages infiltrate the injured site. Neutrophils are the first to arrive; they remove cell debris by releasing free radicals and proteases as well as secreting pro-inflammatory cytokines that stimulate the arrival of macrophages. There two different classes of macrophages arriving at the injured site: M1 (expressing CD68) and M2 (expressing CD163). The M1 class is responsible for producing a high concentration of pro-inflammatory cytokines, which promote further tissue inflammation. Arriving next, is the M2 class of macrophages that induce angiogenesis and tissue remodelling and repair, by activating stem cells. This phase of inflammation is critical to the muscle regeneration process. Experiments have shown that if the inflammation response is inhibited, then muscle repair cannot occur at all. Nevertheless, there must be a balance between insufficient and excessive inflammation response. The regenerative phase is achieved by the activation, proliferation and differentiation of satellite cells that fuse together to form multinucleated myotubes. This is regulated by the presence of a number of growth factors such as insulin-like growth factor-1 (IGF-1), hepatocyte growth factor (HGF) and others. The final phase of the regenerative process is ‘remodelling and repair’ and it involves the remodelling of connective tissue, angiogenesis and functional recovery of the skeletal muscle. How does this happen? Well, once the muscle is injured, there is an excessive production of collagens that promote scar tissue to form. This is so-called fibrosis formation is activated by transforming growth factor-? 1 (TGF-? 1), which plays a major role in this cascade. This phase is over once the injured muscle has been replaced by a functional and contractile apparatus. Figure 1: [pic] Fig. 1 shows the steps involved for a satellite cell to form a myotube. (www. bioscience. org) The role of satellite cells: Satellite cells (identified using electron microscopy) are located under the basal lamina and are a type of muscle stem cells. They are present in muscle tissue in the quiescent form and can be activated by both physiological stimuli (such as extensive exercise), as well as pathological conditions (injury or degenerative disease). Their main function is to create a population of myoblasts that can fuse with each other or with other myofibers and differentiate, so as to repair muscle tissue. Both quiescent and active satellite cells express the transcription factor Pax-7 that is thought to drive transcription and maintain proliferation. Even though the role of Pax-7 is not completely understood, it is evident that without it, we would not have satellite cells. In fact, an experiment showed that mice lacking Pax-7, did not survive beyond 2 weeks. In addition, activated satellite cells express a protein called myogenic regulatory factor (MyoD), which is a crucial factor in regulating the differentiation of muscle cells. Impact of ageing in muscle degeneration: Hypothetically, even though the number of satellite cells decreases with age, the few cells remaining should be enough to initiate the regenerative mechanism. However, experiments have shown that the surrounding tissue and systemic environment to which the satellite cells were placed, were far more important factors for muscle regeneration than the number of cells present. This hypothesis was supported by the fact that old muscle tissue could be regenerated when it was placed in a young animal, but the opposite did not occur. Therefore, the hypothesis that the decrease in satellite cell numbers due to ageing was the major factor that affected regeneration was proved to be wrong. Figure 2: [pic] Fig. illustrates the difference between a normal myofiber and a regenerating myofiber. (www. bioscience. org) Conclusion: All in all, sarcopenia alters the regeneration and repair of muscle, which can cause structural abnormalities. Ageing causes a dramatic decrease in satellite cell numbers and reduces their ability to repair damaged muscle. Even though young stem cells applied to aged or damaged skeletal muscle seem to be promising for therapeutic applications, we must gain a better understanding of satellite cell biology in order to use regenerative medicine to treat sarcopenia. Bibliography: Carosio, S. , Berardinelli, M. G. , Aucello, M. , Musaro, A. (2011) Ageing research reviews. Impact of ageing on muscle cell regeneration. 10: 35-42 Kierszenbaum, A. L. , (2007) Histology and cell biology: An introduction to pathology (2nd Ed. ). Philadelphia: Mosby. 7: 197-210 Crowe, J. , Brdashaw, T. (2010) Chemistry for the Biosciences. The essential concepts. (2nd Ed) Oxford University Press. 9(3): 270-272 Satellite Cells. [Online]. Available from: http://www. brown. edu/Courses/BI0032/adltstem/sc. tm [Accessed 6 December 2011] Zammit, S. P. , et al (2006) Pax7 and myogenic progression in skeletal muscle satellite cells. [Online]. Available from: http://jcs. biologists. org/content/119/9/1824 [Accessed 7 December 2011] Seime, A. , Caron, A. Z. , Gremier, G. (2009) Frontiers in Biosciences:Advances in myogenic cell transplantation and skeletal muscle tissue engineering. [Online]. Available from: http://www. bioscience. org/2009/v14/af/3431/fulltext. asp? bframe=figur es. htmdoi=yes [Accessed 7 December 2011] Word count: 747 How to cite Skeletal Muscle Undergoes Repair and Regenaration Throughout, Essay examples

Emotional Impact of Separation on Hills free essay sample

Before authoring â€Å"Hills like White Elephants,† Hemingway had been residing in Paris with his wife Hadley and son, Bumby. During their stay in Paris, Hadley and Ernest Hemingway met a woman named Pauline Pfeiffer. Pauline was more of a friend to Hadley than Hemingway was. Pauline did not think much of Hemingway at first, she thought he was lazy and a no-doer. Later Pauline and Hemingway fell in love and had an affair. Once Hadley knew of their affair, Hemingway requested a divorce. Hadley agreed under one condition, Hemingway and Pfeiffer had to separate for 100 days. After the 100 days if they were still in love, then Hadley would grant the divorce (Baker 174). This separation period left an indelible effect on Hemingway’s life and works. During this separation, Hemingway began a collection of short stories titled â€Å"Men without Women.† Hemingway explained, â€Å"The title was an indication that all the stories were missing the softening feminine influence† (Baker 182). We will write a custom essay sample on Emotional Impact of Separation on Hills or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Out of this collection, he wrote a short story, â€Å"Hills like White Elephants.†The story opens up with two people engaging in a conversation at a cafà © in a train station. The reader can easily view that the couple is merely just passing time. However, several references could lead the reader to believe that the alcohol consumption is a panacea for the couple. In the opening paragraph, the couple is getting off the train. They wanted to get something to drink. The couple could have had any beverage to drink but the man suggested they drink beer and then he emphasized â€Å"big† ones. This was an indication that the couple was dealing with something serious. In paragraph 87 when the girl did not want to talk anymore, she then asked if they could have another beer (Stanford 841). It is human nature to avoid problems, as this couple is doing. Why do people drink? People develop dependencies, to cope with troubles. In relation to Hemingway, he was among the many literary writers who were alcoholics. He even said, â€Å"That all good writers are drinking writers† (Benedictus). Looking at the circumstances when Hemingway wrote the story, he was very depressed. He became so emotionally depressed he vowed to kill himself by Christmas if his love affair had not settled (Baker 176). He faced guilt for divorcing Hadley. He also faced criticism and rejection from his parents. They did not grant approval to his literary works. Hemingway’s mother had even referred to one of his works as, â€Å"One of the filthiest books of the year† (Baker 180).

Nike an Ethical Issue I Essay Example

Nike an Ethical Issue I Paper Nike an Ethical Issue Nike an Ethical Issue Nike is a company that was created on an agreement and a handshake between two men. That handshake between Bill Bowerman and Phil Knight became the foundation of how Nike does business. Integrity and commitment to the highest ethical standards make up the code of business ethics for Nike. A company like Nike that has a code of ethics and a foundation of how business is conducted should not have any problems with ethical issues as far as the way they do business; however there is an ethical issue in regards to Nike. Ethical Issue Nike has been accused of using child labor in the production of their soccer balls. This ethical issue has taken place in Pakistan. There are laws in Pakistan against child labor and slavery, but the Pakistan government does not take the necessary action to stop it. The United States constitution states that child labor is an illegal and inhumane practice and any United States company found guilty practicing and encouraging it will be prosecuted. The General Agreement on Tariffs and Trade and the World Trade organization prohibits member nations like the United States, from discriminating against the importation of goods made by children. We will write a custom essay sample on Nike an Ethical Issue I specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Nike an Ethical Issue I specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Nike an Ethical Issue I specifically for you FOR ONLY $16.38 $13.9/page Hire Writer In essence it seems as if this practice is condoned. One of the reasons the practice of using child labor goes on is the fact that these third world countries are in such dire need and these children are helping in the support of their families. Pakistan has a per-capita income of nineteen thousand dollars per year. This equates that a typical person lives off of five dollars a day. Nike does not launch production directly in Pakistan. It is subcontracted through a local firm, which has to abide by Nike’s international rules and regulations when producing its goods. Nike has the duty to monitor the subcontracted firm. Nike an Ethical Issue Nike also has based its operations in Vietnam, China, Indonesia, Bangladesh, and India. It seems as if Nike thrives to operate in such countries due to the low cost labor to make its products. Twelve- year-old girls work in Indonesia sweatshops seventy hours a week making Nike shoes in unhealthy plants. There have been many other claims about the mistreatment of workers of sweatshops in other countries in which Nike has subcontracted. Ethical Perceptions across Cultures. The ethical perceptions across the cultures in regards to child labor come from the various sources. The culture for countries such as Pakistan, in which the earnings of one person goes to feeding ten people, it is very difficult for a low income population to survive. With the population in Pakistan being at one million and is an important center for the production of goods for export to international markets. In 1994 exports brought three hundred eighty five million dollars to the economy of Pakistan. Those exports came largely from the use of child labor producing goods. Therefore that culture is somewhat dependent upon those children that work illegally. Looking at the situation from a culture such as the United States, we view it differently. The economy as bad as it may seem it is nothing of that of other countries. The United States is rich in comparison and does not condone such practices. The idea that Nike using child labor open debate as to what is ethically right. Some would say that Nike is doing a great deed for Pakistan. The parents willingly send their children off to work in a factory to help support them so the argument along with that would be to buy more products that the children produce. This would increase their demand and they would produce more. This would allow them to earn more. It is believed this would give them a chance to rise above poverty level and the benefits would not only pay off for the families of the children, but for the nation as well. The argument to increasing the demand of the products made by child labor would be that it encourages child labor. That in turns encourages more birth rates, which creates more slavery, and sweatshops. Education among children will continue to decline. More and more children will be bought and sold on the black market and the problem would never end. Risk and consequences associated. There are many risk and consequences involved with Nike conducting business utilizing child labor around the world. This places a negative impact on Nike and it goes against what is written in the code of conduct for Nike. This could also cause a decrease in sales and a loss in revenue due to the American public opposing this type of practice in business. Conclusion Nike is a business that was built on good values and ethics. Those same values and ethics are in question in regards to the labor they use in third world countries. This labor comes in the form of children. Children are sent to work in these factories by their parents so they can help support them. These children receive very low wages and the working conditions are substandard. There are laws and regulations that govern these practices but they are not strongly enforced. These countries are very poor and the income that Nike brings to these countries drastically improves their economy. The United States constitution states that child labor is an illegal and inhumane practice and any United States company found guilty practicing and encouraging it will be prosecuted. The General Agreement on Tariffs and Trade and the World Trade organization prohibits member Nike, an Ethical Issue nations like the United States, from discriminating against the importation of goods made by children. Nike did not directly have these children working in these conditions. They hire subcontracting firms to make their products. Nike is responsible to monitor the subcontracting firms to ensure all business practices are within the rules and regulations set forth. The ethical perception across the cultures varies among the cultures. The third world countries view this as a means of providing for their families and improving the economy of their countries. Others view this act as unethical and criminal. Nike has taken risk in their production of products in which the use of child labor is used. This risk not only cost them their reputation but it prove to be a huge financial loss as well. References Websites www. American. edu/TED/nike. htm www. nikebiz. com

The Counseling Administration

The Counseling Administration and ethical convictions of a client. Clients Ethic Women have an ethical responsibility for their own lives, and only in urgent cases, when the abonent cannot do that, the consultant is entitled to take temporary responsibility for their lives. The purpose of counseling is to help the clients make a positive responsibility for themselves and their relatives. In modern society, people often appear in a situation of shortage of communication and loneliness, looking for a contact to share their experiences and challenges. In order to open the way to a true dialogue with the woman who needs help, you need, first of all, to be fully accessible to her without constraint, concealment and bias. Presence in dialogue means linguistic conformity and identity. Some centers use the consultative talks slang. The consultant should know and understand the jargon, as they can open the way to empathic relationship with the abonent. However, the content side of the jargon is limited, using it, it is impossible to achieve meaningful changes. The application of the consultant is only to achieve initial understanding. As soon as it appears, you should move away from using jargon synonyms or related words from the arsenal of the regulatory language, the importance of which for further positive change is significantly higher. Some women commonly use terms of psychology and psychiatry to describe their condition, such as "stress", "depression", "phobia", "addiction", etc. They should be taken, but after that systematically encourage the person to describe her condition or desired objectives in concrete terms of action ("see", "hear", "feel", "I want"). For example, the description of the specific features of depression makes them visible, tangible, and measurable, that is more accessible to awareness. It also creates an opportunity for distanced perception. Then the most significant for the women signs of depression, such as fear, are translated into action ("What are you afraid of now?"). The consultation dialogue plays a significant role in contextual issue. It can perform, often against the will of communicant, a variety of functions, such as: to blame to advice to assign responsibility to create comfort, to create tension to oppose, to give orders, to protect etc.Using open-ended questions is the best form of consultative conversation. They allow the women to reveal their feelings and concerns, give them freedom to respond in a way that they prefer. Such questions help the abonent to understand the situation. ("What is your feeling?", "How you reacted to what happened?" Etc.). Questions that begin with "what" and "how" encourage women to extend the joint discussion of problems and feelings, clarify complex situation. Consultants usually avoid questions that begin with "why" - "Why do you have an idea of suicide?", "Why did you decide to call us?". On these issues, there is a hidden reproach, blame or censure (Brown, 2007). Telephone conversation is different from full-time counseling conversation because in a telephone dialogue nonverbal bodily movements are excluded. The particularly important characteristics of different voices are the tone, volume, tempo, timbre. During the dialogue, be sure to monitor compliance with verbal expressions and intonation interlocutors. Intonation and modulation of voice truly reflect the emotional state of a person using fixing on her feelings. Psychological support for women is based on the principles of anonymity, absolute openness and accessibility, privacy, which contributes to the establishment of trust and friendly dialogue, aimed at mobilizing the intellectual, spiritual and physical resources of the individuals in order to overcome their crisis. The consultant must maintain a high degree of reflexivity, monitoring, as the state of the society, and for our own. The necessity and usefulness of such services is sufficiently proved with international experience, and the fact that the number of services and outstanding people in them continues to grow, and have subscribers who say a grateful "thank you" for the fact that they live on, for their help in resolving any problem, for the preservation of the family. The very few people address the professional help of counseling centers There are some reasons, one of which is the lack of awareness about their operation. Advertising often only discourage potential abonent, as presents the service as the treatment of pathologies. Thus, a person feels herself a patient, sick person. The media spread information according to which, to ask for help means that people get ready to template solutions to your problem. This contradicts the basic principle of social work - the principle of individual help.

Dark Ages in the Western Europe Essay Example | Topics and Well Written Essays - 1250 words

Dark Ages in the Western Europe - Essay Example There were constant battles amongst Lords from all over Europe. (Paul B. Newman 121-124). This was as a result of Rome having been in power for a very long period of time, that is, 700 years. The emperor was the ruler of everything. This is what stimulated individuals to wage war in a bid of rising to power and land acquisition. The fighting had various adverse effects among them being destruction of the resources and stagnation of the cultural growth. In addition to this, it is inevitable in any fighting, there were lots of lives of innocent individuals that were lost in battle as the Lords fought with each other to quench their thirst and hunger for power and land. This resulted in children losing their parents, husband losing their wives and vice-versa and so forth. As a result of the lives lost, there was a decrease in the population which in turn led to economic depression. This is because the merchants and traders had reduced number of people that would buy their goods. This le d to the accumulation of their products hence resulting in merchants and other traders operating at a loss.Another issue was to do with reduced attention given to buildings in terms of expansion and architectural development (Morris Berman pg 14-15). It is until the 8th century that there arose a renewed interest in the Romanesque architecture.In terms of technology, despite of the notable positive impacts that come with it, there was retarded development. There was insignificant contribution by scientists

Consumer Adoption of Hybrid Car Technology Dissertation

Consumer Adoption of Hybrid Car Technology - Dissertation Example This section will investigate vehicle registration data and predictions of consumer demand based upon the Thatchenkery analysis (2008) unless otherwise noted, factual attributions in this section of the study will be conclusions drawn from Thatchenkary 2008. From this article, further pressing questions will be addressed relating to consumer choice of hybrid automobiles and the obstacles towards greater market penetration. These questions can be divided between internal factors and external ones relating to consumer choice. The internal questions would relate more to ideological choices encouraging the purchase of a hybrid vehicle, and whether or not the structure and utility of the vehicle is pleasing to a given individual. External questions relate to socioeconomic factors affecting society as a whole. Can the economy and infrastructure of most industrialized countries be converted to support this innovation? How soon? And at what cost? A detailed analysis is necessary in order to identify the pros and cons of hybrid automotive technology and determine the benefits and consequences of government subsidies of the same. Various incentives and tax credits are under consideration by government agencies for the purpose of subsidizing a transition to hybrid vehicle or technology. An analysis of the available technical literature is required in order to determine the success of the subsidy programs, and the likelihood of any unintended consequences that might be detrimental to other sectors of the economy. And whether the widescale implementation of hybrid automobiles can be realized to a great enough extent to achieve both the goals of transportation, and the reduction of greenhouse gas emissions. When the decision is made by government to subsidize hybrid electrical vehicles, the decision invites analysis concerning the form and implementation of the subsidies. Among the issues that this analysis will explore, is the question on whether government subsidies in the form of income tax credits represents a more powerful incentive towards the purchase of hybrid vehicles as opposed to an incentive based on sales tax. The effectiveness of various government incentive programs will be evaluated in light of hybrid purchases, and overall efficiency in a world of rising gasoline prices. This analysis will also seek to identify variations in the demand among consumers as it pertains to the hybrid automobile market. This will be compared against the effectiveness of various government subsidy programs to develop a more thorough picture of the best means by which to promote hybrid automotive technology. It is also necessary to evaluate the effect of convenience of the vehicle compared with the desirability of incentives. Can a government subsidy for hybrid vehicle or purposes enhance sales even in cases where the vehicle might seem less convenient? How important is the comfort and utility of the vehicle compared with the possible incentives of some form of sales tax subsidy, or advantage in regards to the individual consumers income tax? Methodology This study is a literature meta-analysis of the concerns and actions resulting from hybrid automotive technology. A comparison of the primary literature, both legal and technical will be utilized to answer fundamental questions regarding hybrid automotive technology. This analysis seeks to evaluate whether current hybrid technologies do represent increased energy efficiency, as well as a reduction in overall

A Walk to Remember by Nicholas Sparks

A Walk to Remember by Nicholas Sparks â€Å"A Walk to Remember â€Å" Nicholas Sparks, one of the New York Time Best Selling Author wrote his third novel entitled A Walk to Remember. It had been published in the year 1999 of October under Warner Books. The book is about the story of a 57 year old guy, and how he found his greatest love back when his seventeen. He tells how this love changes him in a way he didnt think he should be. The novel is written dedicated to his family, especially to his sister Danielle Sparks Lewis who become his inspiration in writing the novel. The story is fictional but some scenes are based on real life situation. He applied the experience of its own sister. Synopsis: The story is about a guy named Landon Carter, who is at the age of 57. It’s about how his life changes back when he was seventeen. He was Landon a reclusive guy, but everything changes when he asked Jamie Sullivan to be his date on their school party. Jamie is a good girl. She always carries a bible and always wore her ugly sweater. They are totally different but love is really great. The day he came to ask Jamie, he didnt know that it will be the start of something new. Something he didnt look forward to happen. On how he fall in love with someone named Jamie Sullivan. Reaction: The first time Ive got interested about A Walk to Remember is when Im in my third year of high school. I always read stories in wattpad and the author always mention it. They said that it was a great movie which inspired them to write their own stories. That time I didnt know it was a novel because they always mentioned it as a movie. I got a chance to watch it during my senior high, indeed it was great. Now, I needed to critic its book. At first, I didnt want to read it because I already know the flow of the story. Whats the use right? But as Ive read the book, I realized that I was so wrong. The movie is truly different from the book. Yes, it has the same concept but the flows of the scenes are entirely different. There are also some scenes that are informational which wasnt shown in the movie. Reading the novel is better than watching its film. You only need to imagine that youre on the story, and imagine everything that is happening. I was astounded on how this novel makes me feel the same emotion when I watch its movie. I even think Ive shown more emotion now that I read it. It feels like it was all brand new. I can still remember this quotation from the book, â€Å"Love is always patient and kind. It is never jealous. Love is never rude or selfish. It does not take offense and is not resentful. Love takes no pleasure in other peoples sins, but delights in the truth. It is always ready to excuse, to trust, to hope, and endure whatever comes. This has been my favorite line from the novel. That wasnt a simple quotation, it has a deeper meaning. It gives as an idea on what we need to do with our life. We must know the real purpose why we are living here, in this place. We are not here to focus on ourselves but for us to be part of the others life. To give them happiness, hope, and wisdom is our role in this world. A Walk to Remember wants us to remind that everything has its own purposes. Our life is always on God’s hand. You just need to have faith in him and surrender everything to him. For sure, everything will takes place. This story show how great can love is. Nothing is impossible that even miracle do come true. Conclusion: A remarkable book had been written again by Nicholas Sparks. He really knows how to touch our hearts. He has showed us the essence of life. On how powerful what we call love, that it can even do some miracle. This novel is a must read one. It has a theme that everyone can relate with. Film Review â€Å"Dead Poet Society† Dead Poets Society is a film directed by Peter Weir. This drama film was shown during 1989 starring Robin Williams. The story shows on how a teacher can live a great impact to his students. And how can he change the perception of his students. He also tells his student on why they need to seize the day. Characters: Protagonist Robin Williams as Mr. John Keating Ethan Hawke as Todd Anderson Robert Sean Leonard as Neil Perry Josh Charles as Knox Overstreet Dylan Kussman as Richard Cameron Allelon Ruggiero as Steven Meeks James Waterston as Gerard Pitts Gale Hansen as Charlie Dalton Antagonist Norman Lloyd as Gale Nolan Kurtwood Smith as Mr. Perry Synopsis: The story started during the time 1959. There is this guy named Todd Anderson who will take his senior high at Walton Academy. Walton Academy is a school for elite which offer prep boarding. Fortunately, his roommate is one of the most promising students at their school. Neil Perry became his roommate and the friend of Neil accepted him in their group. They are Calm Knox, Richard Cameron, Steven Meeks, Gerard Pitts, and Charlie Dalton. At the first day of their class, they were surprised by Mr. John Keating. He is their new teacher in English which is an alumnus of Walton. This educator has a different way of teaching his student. While having their lesson, he asked his students to stand on the desk, he even let them walk in a courtyard with their own way. Keating also instruct them to reap out the pages of their book in poetry. He was the one who motivated the boys to see the world in a different perspective and seize every day of their life. Reaction: Gather ye rosebuds while ye may. The Latin term for this is carpe diem means seize the day. An extraordinary life to be with, an abundant life. A movie that turns some of my perceptions upside down. Not a simply film but a wake-up call for everyone. A call for makeover. I adore Dead Poets Society for the reason that beyond the appearance is the thought of passion and a purpose driven life. It thought me that achieving all of my goals in life is not just the center of everything because if there is a great things surely there will also be greater and greatest things in life. Invisible by naked eyes but clearly seen by the heart. Just what Mr. Keating said, Yes indeed it is a battle of war and the casualties could be our hearts and souls. I was amazed at every scene because it was my first experience watching a film wherein my focus is not on the characters but what they want to import. I was also caught by this question, What will your verse be? Really, I meditate these words and asked myself if what verse I can contribute to this play. To learn from the experience of the past, to forget what is behind and to savor every moment. Poetry is more than poetry, beyond them is the life. One of the lessons I learn is that we do have different voices and I must strive to find my own voice. Maybe some people find the Dead Poets Society film a weird one but for me as I focus my attention on it, thousands of my emotions is on slide and I cant explain it through words but all I can express is that it is splendid. We must seize every step we take. In our final moments we all realize what life is all about. Dont wait until youre on your deathbed to figure out what matters most. To look things in different way, it’s not really a risk but an adventure and maybe by trying the things we thought is silly can be the better one. Stop acting and show who we really are and what the desires of our hearts are. We can go anywhere and can do anything and were not trapped in this life. Conclusion: I have watched many films but this one is something different. Tough I may say that the quality of the movie is not that good, maybe because it has been shown long time ago, but the message they want to convey is clear. It is something we need to remember and apply in our daily life. It was so interesting, touching, and knowledgeable. As a future mentor, we must really watch this kind of movie. This movie will help educator to understand his/her students. It will give us idea on how to handle and how to have a good relationship with your students. Someday, when I become a teacher, I will try my best to be Mr. John Keating to my class.