Tuesdays with Morrie Essay - 659 Words

At first glance, the movie, Tuesdays With Morrie, appeared to be a movie about an ex-student learning a final lesson about life from his dying ex-professor. But, as the movie progressed, I felt it was actually a movie about two dying men. Morrie, the old professor, was in the final stages of ALS and physically dying. Mitch, the former student was a commitment-phobic living an unfulfilled life and spiritually dying. Spiritual death is reversible, so Mitch tried to gain some of the wisdom and learn some of the lessons that Morrie had already learned in his happily fulfilled life. On the other hand, physical death is irreversible and Morrie realized that his time was growing short. He had concerns, such as becoming increasingly dependent on†¦show more content†¦In fact, his job was his main priority. Maybe he was afraid to face his fears and kept his mind off of them by absorbing himself in work. But, Morrie made Mitch face those fears, taught him that love was the most importa nt and powerful force in life and without it, we’re nothing. Mitch ultimately realized that his priorities were backwards and sought more meaning in his life. He learned to take time for others, especially Janie, and show affection. Love and commitment no longer scared him and he was able to savage his relationship. Morrie essentially saved Mitch’s relationship with Janine and made him realize that there was more to life than just work. nbsp;nbsp;nbsp;nbsp;nbsp;Mitch helped improve Morrie’s final days because he was very ill and required physical and emotional help. Physically, he was unable to do things like move, dress himself or even cough. He feared loosing his independence. But, Mitch, his wife and his caretakers relieved those fears. They helped him with his physical and emotional needs. He was constantly surrounded by people, who loved and cared for him. In a way, he was able to live the life he had through Mitch. Everyone needs someone to talk to and Morrie was no exception. Conversations with Mitch forced him to think about some of the adversities in his own life such as his strained relationship with his father. Morrie’s father had been a cold, distant man who easily detached himself from people. His detachment was evident when heShow MoreRelatedTuesday with Morrie2551 Words   |  11 PagesAlbom, and Morrie who is the main subject. Their relationship starts when Mitch is in college while Morrie is his sociology professor. Morrie seems to be a man who wants to leave a legacy behind after he dies since he has been told by the doctor that his life is coming to an end. Mitch considers it a privilege meeting someone who teaches about life and offers solutions to life challenges. As Morrie happens to meet with Mitch, his past student and friend, they plan to start meeting on Tuesdays and MitchRead MoreTuesdays With Morrie By Morrie1882 Words   |  8 Pages Tuesdays with Morrie tells th e real story of Morrie Schwartz. Morrie was a university professor who was dying of ALS (Lou Gehrig s disease). Instead of being afraid of death, he faced it head on and decided to make the most of his time left. After seeing a Nightline episode featuring his old professor, Morrie, the author, Mitch, decides to pay his old professor a visit. Mitch is intrigued by Morrie s attitude towards death and his life lessons, so he decides to visit Morrie again next TuesdayRead MoreTuesdays with Morrie Essay1074 Words   |  5 PagesCameron, discuss how effectively Mitch Albom, author of Tuesdays with Morrie, uses plot and story, character development, point of view, theme, and symbols to convey his mesage. Include your personal thoughts and views, as well as textual references, to support your opinions. In Mitch Albom’s Tuesday’s with Morrie, Albom detailed his personal experiences with his professor Morrie Schwartz. Mitch also expressed how influential Morrie was to his friends, relatives, patients, and coworkers. WithinRead MoreTuesdays with Morrie Essay1149 Words   |  5 PagesTuesdays with Morrie. The symbolic interactionism is an excellent sociological perspective that allows us to focus on micro activities and to analyze our society which is the product of everyday’s life. Tuesdays with Morrie is more than a simple book, more than a romance one; it is a great book that teaches us many of life’s greatest lessons. An analysis of this book using the SI perspective and concepts such as meaning making, status, impression management, looking-glass self, role taking, roleRead MoreTuesdays with Morrie Essay812 Words   |  4 PagesThe focus throughout Tuesdays with Morrie was on life. Many might see it as the story of death, but it is actually the story life. Morrie might talk a little on how he meets death, but what he is talking about is living at the end of his life. Mitch writes, â€Å"Now here we were . . . . . . Dying man talks to living man, tells him what he should know.†(Albom, 133) When a timer is placed on Morrie’s remaining days, he obtains a dying man’s perspective on what is truly important in life, and how to incorporateRead MoreTuesdays With Morrie Analysis771 Words   |  4 Pageshad kept hidden†(Albom 64). This quote is from Tuesdays with Morrie, It is talking about how the main character Mitch Albom puts himself in Morries Schwartz’s shoes. Morrie had a disease called Amyotrophic Lateral Sclerosis, a nervous system disease that weakens muscles and impact physical functions. Morrie is Mitch’s old college professor. They meet on tuesdays at Morries house to talk about his life lessons that he has learned over his lifespan. Morrie teaches people to live through loving what heRead MoreSummary Of Tuesdays With Morrie1487 Words   |  6 PagesTuesdays with Morrie was awakening, yet, heartbreaking and I couldn’t put the book down. It was a story of friendship that turned to love, a story of family, a story of trust, and a story of death. As I read each page, I felt closer to Morrie Schwartz as if I knew him personally. Morrie, the main character in the book, was a kind, sensitive soul. He believed in humanity, and enjoyed sharing his wisdom with others. As a sociology professor at Brandeis University he taught and mentored many studentRead MoreEssay on Tuesdays with Morrie577 Words   |  3 PagesTuesdays with Morrie The setting is late of 1979. A young boy visits with an elderly man every Tuesday to be enlightened on the meaning of life. His name is Mitchell, but friends call him ?Mitch.? The greatest lesson of life is life. Professor Morrie Schwartz is a special teacher, not only is he an instructor, but a mentor and a friend. He is a small elderly man with thin gray hair who dresses casual in old gray sweatshirts. Morrie was a dancer and also a prominent doctor of sociology. He wasRead MoreSummary Of Tuesdays With Morrie1945 Words   |  8 PagesAphorism Narrative Aphorisms are statements of observations that express an opinion or remarks of wisdom. Tuesdays With Morrie is a book about a man who’s dying from ALS, or Amyotrophic Lateral Sclerosis which is a â€Å"progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord.† (What Is ALS?) Morrie uses aphorisms quite frequently to accept his future and make peace with the past. The two aphorisms I chose are about making your life as fulfilling as possibleRead MoreTuesdays With Morrie Character Analysis707 Words   |  3 Pagesso afraid to show their emotions? In the book Tuesdays with Morrie, there is a man named Morrie who teaches people to be more open rather than afraid to give their love to others, and to be able to receive ones outgoing love. Morrie teaches Mitch showing his emotions is natural and it’s what every living thing does. Morrie tells his student Mitch â€Å"The most important thing in life is to learn how to give out love, and let love come in.†(Albom 53) Morrie says â€Å"people should not be scared or nervous

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Skeletal Muscle Undergoes Repair and Regenaration Throughout Free Essays

|21 | Coursework R: Mini-Review Topic Selected: Topic 2: â€Å"Skeletal muscle undergoes repair and regenaration throughout normal life. Write a review on the processes involved, emphasizing the role of satellite cells. † Muscle Cell Regeneration and the Impact of Ageing Introduction: Throughout normal life, skeletal muscles undergo repair and regeneration in response to injury through a process involving several sequential steps. We will write a custom essay sample on Skeletal Muscle Undergoes Repair and Regenaration Throughout or any similar topic only for you Order Now A very important role in this regeneration is played by satellite cells, which are small mononuclear progenitor cells found in mature muscle tissues. In this review, we are going to explore the consequences of ageing in satellite cell numbers and their ability to maintain and preserve muscle tissue. Steps involved when skeletal muscle is damaged: The homeostatic process that allows muscle regeneration in response to an injury stimulus, involves four interrelated steps: degeneration, inflammation, regeneration and remodelling repair. When myofibers are damaged, extracellular calcium flows into the cell, initiating proteolysis, which causes necrosis. The necrosis of myofibers brings about an inflammatory response where neutrophils and macrophages infiltrate the injured site. Neutrophils are the first to arrive; they remove cell debris by releasing free radicals and proteases as well as secreting pro-inflammatory cytokines that stimulate the arrival of macrophages. There two different classes of macrophages arriving at the injured site: M1 (expressing CD68) and M2 (expressing CD163). The M1 class is responsible for producing a high concentration of pro-inflammatory cytokines, which promote further tissue inflammation. Arriving next, is the M2 class of macrophages that induce angiogenesis and tissue remodelling and repair, by activating stem cells. This phase of inflammation is critical to the muscle regeneration process. Experiments have shown that if the inflammation response is inhibited, then muscle repair cannot occur at all. Nevertheless, there must be a balance between insufficient and excessive inflammation response. The regenerative phase is achieved by the activation, proliferation and differentiation of satellite cells that fuse together to form multinucleated myotubes. This is regulated by the presence of a number of growth factors such as insulin-like growth factor-1 (IGF-1), hepatocyte growth factor (HGF) and others. The final phase of the regenerative process is ‘remodelling and repair’ and it involves the remodelling of connective tissue, angiogenesis and functional recovery of the skeletal muscle. How does this happen? Well, once the muscle is injured, there is an excessive production of collagens that promote scar tissue to form. This is so-called fibrosis formation is activated by transforming growth factor-? 1 (TGF-? 1), which plays a major role in this cascade. This phase is over once the injured muscle has been replaced by a functional and contractile apparatus. Figure 1: [pic] Fig. 1 shows the steps involved for a satellite cell to form a myotube. (www. bioscience. org) The role of satellite cells: Satellite cells (identified using electron microscopy) are located under the basal lamina and are a type of muscle stem cells. They are present in muscle tissue in the quiescent form and can be activated by both physiological stimuli (such as extensive exercise), as well as pathological conditions (injury or degenerative disease). Their main function is to create a population of myoblasts that can fuse with each other or with other myofibers and differentiate, so as to repair muscle tissue. Both quiescent and active satellite cells express the transcription factor Pax-7 that is thought to drive transcription and maintain proliferation. Even though the role of Pax-7 is not completely understood, it is evident that without it, we would not have satellite cells. In fact, an experiment showed that mice lacking Pax-7, did not survive beyond 2 weeks. In addition, activated satellite cells express a protein called myogenic regulatory factor (MyoD), which is a crucial factor in regulating the differentiation of muscle cells. Impact of ageing in muscle degeneration: Hypothetically, even though the number of satellite cells decreases with age, the few cells remaining should be enough to initiate the regenerative mechanism. However, experiments have shown that the surrounding tissue and systemic environment to which the satellite cells were placed, were far more important factors for muscle regeneration than the number of cells present. This hypothesis was supported by the fact that old muscle tissue could be regenerated when it was placed in a young animal, but the opposite did not occur. Therefore, the hypothesis that the decrease in satellite cell numbers due to ageing was the major factor that affected regeneration was proved to be wrong. Figure 2: [pic] Fig. illustrates the difference between a normal myofiber and a regenerating myofiber. (www. bioscience. org) Conclusion: All in all, sarcopenia alters the regeneration and repair of muscle, which can cause structural abnormalities. Ageing causes a dramatic decrease in satellite cell numbers and reduces their ability to repair damaged muscle. Even though young stem cells applied to aged or damaged skeletal muscle seem to be promising for therapeutic applications, we must gain a better understanding of satellite cell biology in order to use regenerative medicine to treat sarcopenia. Bibliography: Carosio, S. , Berardinelli, M. G. , Aucello, M. , Musaro, A. (2011) Ageing research reviews. Impact of ageing on muscle cell regeneration. 10: 35-42 Kierszenbaum, A. L. , (2007) Histology and cell biology: An introduction to pathology (2nd Ed. ). Philadelphia: Mosby. 7: 197-210 Crowe, J. , Brdashaw, T. (2010) Chemistry for the Biosciences. The essential concepts. (2nd Ed) Oxford University Press. 9(3): 270-272 Satellite Cells. [Online]. Available from: http://www. brown. edu/Courses/BI0032/adltstem/sc. tm [Accessed 6 December 2011] Zammit, S. P. , et al (2006) Pax7 and myogenic progression in skeletal muscle satellite cells. [Online]. Available from: http://jcs. biologists. org/content/119/9/1824 [Accessed 7 December 2011] Seime, A. , Caron, A. Z. , Gremier, G. (2009) Frontiers in Biosciences:Advances in myogenic cell transplantation and skeletal muscle tissue engineering. [Online]. Available from: http://www. bioscience. org/2009/v14/af/3431/fulltext. asp? bframe=figur es. htmdoi=yes [Accessed 7 December 2011] Word count: 747 How to cite Skeletal Muscle Undergoes Repair and Regenaration Throughout, Essay examples

Emotional Impact of Separation on Hills free essay sample

Before authoring â€Å"Hills like White Elephants,† Hemingway had been residing in Paris with his wife Hadley and son, Bumby. During their stay in Paris, Hadley and Ernest Hemingway met a woman named Pauline Pfeiffer. Pauline was more of a friend to Hadley than Hemingway was. Pauline did not think much of Hemingway at first, she thought he was lazy and a no-doer. Later Pauline and Hemingway fell in love and had an affair. Once Hadley knew of their affair, Hemingway requested a divorce. Hadley agreed under one condition, Hemingway and Pfeiffer had to separate for 100 days. After the 100 days if they were still in love, then Hadley would grant the divorce (Baker 174). This separation period left an indelible effect on Hemingway’s life and works. During this separation, Hemingway began a collection of short stories titled â€Å"Men without Women.† Hemingway explained, â€Å"The title was an indication that all the stories were missing the softening feminine influence† (Baker 182). We will write a custom essay sample on Emotional Impact of Separation on Hills or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Out of this collection, he wrote a short story, â€Å"Hills like White Elephants.†The story opens up with two people engaging in a conversation at a cafà © in a train station. The reader can easily view that the couple is merely just passing time. However, several references could lead the reader to believe that the alcohol consumption is a panacea for the couple. In the opening paragraph, the couple is getting off the train. They wanted to get something to drink. The couple could have had any beverage to drink but the man suggested they drink beer and then he emphasized â€Å"big† ones. This was an indication that the couple was dealing with something serious. In paragraph 87 when the girl did not want to talk anymore, she then asked if they could have another beer (Stanford 841). It is human nature to avoid problems, as this couple is doing. Why do people drink? People develop dependencies, to cope with troubles. In relation to Hemingway, he was among the many literary writers who were alcoholics. He even said, â€Å"That all good writers are drinking writers† (Benedictus). Looking at the circumstances when Hemingway wrote the story, he was very depressed. He became so emotionally depressed he vowed to kill himself by Christmas if his love affair had not settled (Baker 176). He faced guilt for divorcing Hadley. He also faced criticism and rejection from his parents. They did not grant approval to his literary works. Hemingway’s mother had even referred to one of his works as, â€Å"One of the filthiest books of the year† (Baker 180).